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KMID : 0360319940260020236
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Journal of Korean Cancer Research Association
1994 Volume.26 No. 2 p.236 ~ p.241
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Identification of Number of Positive Axillary Nodes to Influence Prognosis in Breast Cancer after Adjuvant CMF Chemotherapy
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임호영
유효민/고은희/유내춘/김주항/노재경/이경식/조인성
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Abstract
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The most important prognostic indicator for patients with operable breast cancer is the histological involvement of axillary lymph nodes metastasis, and the extent of nodal metastasis is highly prognostic, larger numbers of positive nodes are
associated
poorer prognosis.
One hundred and nine patients of resected breast cancer with nodal involvement treated at Yonsei University College of Medicine from Dec. 1980 to Dec. 1989 were studied to identify the number of positive axillary nodes to influence prognosis
after
adjuvant CMF chemotherapy. And we obtained the following results.
There was no significant difference in the disease free survival and overall survival between those with 1-3 positive axillary nodes and those with 4~7 positive nodes. So, we tried to reassess positive nodal groupings for determining the
prognosis
of
breast cancer and identifying high risk group according to their nodal status. The current results showed that there was a significant difference in the disease free survival and overall survival between those with 1~7 positive axillary nodes and
those
with ≥ 8 positive nodes(DFS; 73% vs. 42%, OS; 78% vs. 40%, p<0.05).
This resport emphasizes the prognostic importance of positive nodal involvement with patients of breast cancer and necessity of intensive managment for those with ≥8 positive nodes.
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KEYWORD
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